Sílvia Busquets Selected Research

N- (3,5- bis(trifluoromethyl)phenyl)- 2- chloro- 4- (trifluoromethyl)pyrimidine- 5- carboxamide

4/2009	Both AP-1 and NF-kappaB seem to be involved in tumour growth in an experimental rat hepatoma.
5/2007	The AP-1/NF-kappaB double inhibitor SP100030 can revert muscle wasting during experimental cancer cachexia.

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Sílvia Busquets Research Topics

Disease

37	Neoplasms (Cancer) 01/2020 - 07/2003
36	Cachexia 01/2020 - 05/2002
14	Hepatocellular Carcinoma (Hepatoma) 01/2020 - 07/2004
14	Ascites 01/2020 - 07/2004
13	Body Weight (Weight, Body) 01/2020 - 01/2005
8	Anorexia 01/2019 - 07/2003
6	Glucose Intolerance 01/2019 - 04/2004
4	Atrophy 01/2020 - 10/2007
4	Lewis Lung Carcinoma 04/2016 - 01/2007
4	Insulin Resistance 07/2012 - 11/2006
4	Obesity 11/2011 - 02/2002
3	Muscular Atrophy (Muscle Atrophy) 01/2020 - 03/2013
3	Weight Loss (Weight Reduction) 12/2014 - 12/2010
2	Inflammation (Inflammations) 01/2017 - 06/2011
2	Wasting Syndrome (Wasting Disease) 07/2012 - 09/2004
2	Hyperthermia 02/2011 - 07/2009
2	Starvation 10/2007 - 06/2002
2	Necrosis 10/2003 - 04/2003
1	Hypertrophy 12/2014
1	Muscle Neoplasms (Neoplasms, Muscle) 07/2011
1	Asthenia 07/2011
1	Type 2 Diabetes Mellitus (MODY) 02/2011
1	Hyperoxia 01/2009
1	Sepsis (Septicemia) 10/2003

Drug/Important Bio-Agent (IBA)

13	Proteins (Proteins, Gene)FDA Link 06/2018 - 05/2002
10	Muscle Proteins (Muscle Protein)IBA 01/2019 - 04/2004
10	CytokinesIBA 11/2011 - 07/2003
8	Formoterol Fumarate (Oxis)FDA Link 06/2018 - 09/2004
5	MyostatinIBA 06/2018 - 12/2009
5	Interleukin-15 (Interleukin 15)IBA 11/2011 - 02/2002
4	UbiquitinIBA 03/2013 - 10/2004
4	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 12/2009 - 07/2003
3	Pharmaceutical PreparationsIBA 09/2019 - 12/2010
3	Proteasome Endopeptidase Complex (Proteasome)IBA 06/2018 - 05/2007
3	AntioxidantsIBA 01/2017 - 03/2005
3	LipidsIBA 02/2011 - 01/2006
3	Messenger RNA (mRNA)IBA 12/2010 - 10/2004
3	EnzymesIBA 03/2010 - 03/2005
3	Transcription Factor AP-1 (Transcription Factor AP 1)IBA 04/2009 - 01/2006
2	Carnitine (L-Carnitine)FDA LinkGeneric 01/2020 - 12/2012
2	Biological ProductsIBA 01/2020 - 09/2011
2	Ligases (Synthetase)IBA 06/2018 - 03/2013
2	Tyrosine (L-Tyrosine)FDA Link 04/2016 - 06/2002
2	Adenosine Triphosphate (ATP)IBA 12/2014 - 03/2013
2	Fatty Acids (Saturated Fatty Acids)IBA 02/2011 - 12/2010
2	Malondialdehyde (Propanedial)IBA 03/2010 - 03/2005
2	N- (3,5- bis(trifluoromethyl)phenyl)- 2- chloro- 4- (trifluoromethyl)pyrimidine- 5- carboxamideIBA 04/2009 - 05/2007
2	NF-kappa B (NF-kB)IBA 04/2009 - 05/2007
2	Uncoupling Protein 3IBA 01/2009 - 02/2006
2	PPAR gammaIBA 01/2008 - 07/2007
2	ResveratrolIBA 04/2007 - 01/2007
1	Adrenergic beta-Antagonists (beta-Adrenergic Blocking Agents)IBA 01/2019
1	Peptides (Polypeptides)IBA 01/2019
1	AndrogensIBA 01/2019
1	GhrelinIBA 01/2019
1	Beclin-1IBA 06/2018
1	Myosins (Myosin)IBA 01/2017
1	Phenylalanine (L-Phenylalanine)FDA Link 04/2016
1	Activins (Activin)IBA 04/2016
1	Sorafenib (BAY 43-9006)FDA Link 01/2014
1	F-Box ProteinsIBA 03/2013
1	Theophylline (Theon)FDA LinkGeneric 08/2012
1	TeaIBA 08/2012
1	Eicosapentaenoic AcidIBA 02/2011
1	CarbohydratesIBA 02/2011
1	amsonic acid (DAS)IBA 02/2011
1	Insulin (Novolin)FDA Link 02/2011
1	Corticotropin-Releasing Hormone Receptors (Corticotropin Releasing-Hormone Receptor)IBA 12/2010
1	Megestrol Acetate (Borea)FDA LinkGeneric 12/2010
1	Complementary DNA (cDNA)IBA 12/2010
1	InterleukinsIBA 12/2009
1	PPAR deltaIBA 07/2009
1	Oxidants (Oxidizing Agents)IBA 01/2009
1	GW 1929IBA 01/2008
1	Sterol Esterase (Hormone-Sensitive Lipase)IBA 12/2007
1	pyruvate dehydrogenase kinase 4IBA 07/2007
1	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 07/2007
1	Ubiquitin-Conjugating EnzymesIBA 05/2007
1	Fish OilsIBA 04/2007
1	Deoxyglucose (2 Deoxy D glucose)IBA 11/2006
1	Glucose (Dextrose)FDA LinkGeneric 11/2006
1	TrioleinIBA 01/2006
1	Oxygen (Dioxygen)IBA 03/2005
1	NitrogenIBA 03/2005
1	CatalaseIBA 03/2005
1	Superoxide DismutaseIBA 03/2005
1	Heme Oxygenase-1IBA 03/2005
1	3-nitrotyrosineIBA 03/2005
1	CalpainIBA 10/2004
1	Caspase 3 (Caspase-3)IBA 09/2004
1	DNA (Deoxyribonucleic Acid)IBA 09/2004
1	factor AIBA 10/2003

Therapy/Procedure

6	Therapeutics 01/2017 - 01/2010
2	Nutritional Support (Artificial Feeding) 01/2019 - 01/2019
2	Drug Therapy (Chemotherapy) 01/2016 - 01/2007
1	Bed Rest (Bedrest) 01/2017
1	Subcutaneous Injections 01/2017
1	Radiotherapy 01/2007
1	Ligation 10/2003
1	Punctures 10/2003